Cergentis' Targeted Locus Amplification (TLA) Technology uniquely enables the targeted complete Next Generation Sequencing of any genomic locus in any genome of interest.


TLA uses the physical proximity of nucleotides within a locus of interest as the basis of selection and requires just one primer pair complementary to a short locus-specific sequence to amplify 10.000's of basepairs of surrounding sequence information.

TLA-based sequencing results in complete sequence information and the detection of all Single Nucleotide Variants & Structural Variants. In combination with short and long read NGS Sequencing, TLA also enables haplotyping.


Cergentis provides kits and services.