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Application notes

Cergentis and its partners have published various application notes about the TLA Technology, its applications and the automation of the TLA protocol. 

  • Gene editing
  • Application note on TLA-based transgene and -integration site sequencing.
    Application note on TLA-based transgene and -integration site sequencing.
  • Gene sequencing & haplotyping
  • Application note on the TLA protocol for isolated genomic DNA.
    Application note on the TLA protocol for isolated genomic DNA.
  • Application Note Pacific Biosciences - Targeted Sequencing and Chromosomal Haplotype Assembly Using Cergentis TLA Technology with PacBio SMRT Sequencing.
    Application Note Pacific Biosciences - Targeted Sequencing and Chromosomal Haplotype Assembly Using Cergentis TLA Technology with PacBio SMRT Sequencing.
  • Automation
  • Application note: Automated Targeted Locus Amplification Technology for Targeted Complete Gene Sequencing using the Janus NGS Express Workstation.
    Application note: Automated Targeted Locus Amplification Technology for Targeted Complete Gene Sequencing using the Janus NGS Express Workstation.
  • CHO cells
  • Application note on the use of the TLA technology in transgene and integration site sequencing in CHO cell lines.
    Application note on the use of the TLA technology in transgene and integration site sequencing in CHO cell lines.
  • Transgenic models
  • Application note on TLA-based transgene and -integration site sequencing.
    Application note on TLA-based transgene and -integration site sequencing.
  • MRD detection
  • Application note on MRD testing using TLA data
    Application note on MRD testing using TLA data
  • Leukemia
  • Application note on the application of TLA in gene fusion detection in pediatric leukemia
    Application note on the application of TLA in gene fusion detection in pediatric leukemia
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