"TLA is a highly efficient method for mapping the insertion site of any transgene.”
"Working with Cergentis and utilizing TLA for genotypic characterization of cell lines for biotherapeutic production has been instrumental in understanding our cell line development strategy and processes. Recently, we have used TLA to determine the cause of unanticipated genotype in several targeted-integration clones. Experiments were conducted aimed at determining the integration site(s) to nucleotide resolution, using genome walking followed by TLA. Our collaboration with Cergentis with productive, yielding a publication and attendance at conferences. Overall, the Cergentis customer service is excellent and their technical team is knowledgeable, reliable and supportive. We look forward to future partnership."
"TLA has become an indispensable tool to characterize transgene insertion events and complex gene targeting approaches."
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Our most popular solutions
CLONALITY ASSURANCE PACKAGE
Service package: TLA combined with breakpoint-based qPCR for rapid, cost-effective clonality assurance of your master cell bank (MCB).
Fully integrated in-house solution for CHO clone selection. Includes reagents kit, wet lab protocol, access to analysis software, scientific consultation & orderable controls.
VECTOR COPY NUMBER DETERMINATION BY DDPCR
Performed either in conjunction with TLA-based service or as a stand-alone QC.