Robust Detection of Translocations in FFPE biopsies with TLA-based NGS: Application in Lymphoma Diagnostics
Currently, lymphoma diagnostics is predominantly performed with fluorescence in situ hybridization (FISH), which is labor-intensive, can be difficult to interpret, and does not always reveal the fusion partner. Alternatives based on next generation sequencing (NGS) are being tested, but the robust detection of structural variants remains a challenge.
In this webinar, our first speaker, Daphne de Jong of Amsterdam University Medical Center, will explain the important role of genetic information in lymphoma diagnostics, as well as the limitations of current technologies.
The second speaker, Bauke Ylstra of Amsterdam UMC, will then present the results of a study performed on more than 100 lymphoma FFPE samples from several clinical sites with a TLA-based panel assay.