Testimonials
Don’t just take our word for it - see what some of our customers say about us.
Don’t just take our word for it - see what some of our customers say about us.
"Working with Cergentis and utilizing TLA for genotypic characterization of cell lines for biotherapeutic production has been instrumental in understanding our cell line development strategy and processes. Recently, we have used TLA to determine the cause of unanticipated genotype in several targeted-integration clones. Experiments were conducted aimed at determining the integration site(s) to nucleotide resolution, using genome walking followed by TLA. Our collaboration with Cergentis with productive, yielding a publication and attendance at conferences. Overall, the Cergentis customer service is excellent and their technical team is knowledgeable, reliable and supportive. We look forward to future partnership."
"We have been working with Cergentis on a number of projects. Each project was carried out timely, precise, and without friction. For sure we are happy customers."
"For the last project that Cergentis carried out for us (random insertion transgenic), a genotyping protocol was developed by our external genotyping partner without issue and homozygous transgenes were identified. This is a significant plus for us to have confidence that the insertion event is not likely to cause any other gene effect, and also to identify homozygotes without test breeding is a big positive in reducing the amount of animals needed for that step."
"Using the innovative TLA approach, Cergentis has mapped the integration sites of transgenes of several mouse lines generated by our team. The customer service was outstanding, and the service was completed professionally. The extended data from the TLA analyses have been instrumental in the design of better genotyping protocols and a variety of subsequent genetic studies."
"TLA has become an indispensable tool to characterize transgene insertion events and complex gene targeting approaches."
"We perform gene editing in primary human immune cells for basic research, drug discovery, and to develop new cell therapies. Cergentis has helped us characterize the on- and off-target integrations when non-virally targeting new genetic material into human T cells with CRISPR, aiding our push towards clinical translation."
"Working with the team at Cergentis has allowed us to add an extra dimension to the analysis of our stable cell lines. Their understanding of our needs combined with the reliability and reproducibility of TLA analysis has resulted in a number of successful projects."
"We worked together with Cergentis and applied TLA-based solutions to facilitate the complete genetic characterization of our vector-producing clones and final medicinal products. By uniquely combining integrity assessment of the entire vector with integration analysis, TLA helped us QC insert integrity throughout the entire production chain and these data completed our clinical study dossier for TEG001. As such, TLA played a key role in helping us establish a valuable framework for future GTMPs. The service of Cergentis was timely, accurate and pleasant."
"TLA analysis has proven to be very useful to quality control genetically engineered cell lines”
"TLA is a highly efficient method for mapping the insertion site of any transgene.”
"Cergentis quickly determined transgene insertion for three out of three lines along with providing information on deletions and rearrangements in chromosomal DNA at the site. The service was quick, accurate and reasonably priced, and reports were complete and helpful.”
"Thank you so much. Data about the structural changes in our patient are very clear. Really powerful technology!”
"TLA outperforms traditional methods used in CHO cell line characterisation and provides higher resolution and sensitivity.”