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Standard Genetic QC ServicesView solutions
Service PackagesView solutions
Cell Line DevelopmentView solutions
Cell & Gene TherapyView solutions
Genetically Engineerd ModelsView solutions
Standard Genetic QC Services
Commercial
- TLA-based transgene and integration site analysis
- Per clonal sample with a single vector
- Standard reporting
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Large (>50KB) or multiple vectors will require additional costs.
For heterogeneous samples with a single vector, analysis costs start at: €3,525 (per sample).
Academic
- TLA-based transgene and integration site analysis
- Per clonal sample with a single vector
- Standard digital reporting
- Guaranteed turnaround time:
- Standard: 10 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks**
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €1,725
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Large (>50KB) or multiple vectors will require additional costs.
For heterogeneous samples with a single vector, analysis costs start at: €3,525 (per sample).
**Additional requirements apply, please contact us for more details.
- Reagents for up to 24 samples
- Shelf-life: 6 months
- TLA-based transgene and integration site analysis in-house
Starting at €9,500
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Service Packages
Package
- MCB characterization, qPCR breakpoint and statistical analysis on subclones**
- Extensive (digital) reporting meets regulatory requirements
- In accordance with ICH Q5D guidelines
- Accepted for regulatory filings
- Pre-finalization report review include
- Guaranteed turnaround time: 12 weeks
- ISO/IEC 17025:2017 accredited*
Optional:
- Expedited turnaround time: 8 weeks
Starting at €30,000
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
**Subclone generation is not included in this package.
Package
- TLA-based genetic stability analysis across various generations (e.g. MCB, WCB 3 generation times, EOP)
- In accordance with ICH Q5D guidelines
- Final conclusions on stability of analyzed cell bank(s)
- (Digital) reporting meeting regulatory requirements
- Pre-finalization report review included
- Guaranteed turnaround time: 8 weeks
- ISO/IEC 17025:2017 accredited*
Optional:
- Expedited turnaround time: 4 weeks
Starting at €25,000
Order now
*TLA processing of cells, NGS sequencing, and data analysis (except for copy number estimation and clonality assessment) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Package
All-in-one:
- Clonality Assurance Package
- Genetic Stability Package
- (Digital) reporting meeting regulatory requirements
- Possibility to review report pre-finalization
- Guaranteed turnaround time: 12 weeks
- ISO/IEC 17025:2017 accredited*
Optional:
- Expedited turnaround time: 8 weeks
Starting at €50,000
Order now
*TLA processing of cells, NGS sequencing, and data analysis (except for copy number estimation and clonality assessment) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Cell Line Development Genetic QC Solutions
Service
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Discriminating highly homologous vectors
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €4,125
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector (basic reporting)
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector (basic reporting)
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Integration site analysis
- Vector integrity assessment in producer cells
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Read: FDA & NIH (2020)
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Large (>50KB) or multiple vectors will require additional costs.
Cell & Gene Therapy Genetic QC Solutions
Service
- Integration site analysis
- Vector integrity assessment in producer cells
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Read: FDA & NIH (2020)
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Integration site analysis
- Vector integrity assessment
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Read: University Medical Center Utrecht (2019)
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Integration site analysis
- Vector integrity assessment
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Read: Memorial Sloan Kettering Cancer Center (2017) or
UCSF (2018)
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Genetically Engineered (Animal) Model Genetic QC Solutions
Service
- Identify integration site(s)
- Assess vector integrity (incl. sequence & structural variant detection)
- Assess structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Optional:
- Genotyping primer design (cost per set)
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Vector integration profile
- Vector integrity (incl. sequence & structural variant detection)
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,025
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.
Service
- Vector integration profile
- Vector integrity
- Structural variations in the host genome at the integration site(s)
- Guaranteed turnaround time:
- Standard: 6 weeks
- Expedited: 4 weeks
- Super expedited: 3 weeks
- Cost per clonal sample with a single vector
- Additional TLA amplification & sequencing with 1 TLA primer pair. Cost per sample (e.g. for vector sequences >50 KB)
- Digital standard report
- Scientific consultation
- ISO/IEC 17025:2017 accredited*
Starting at €3,575
Order now
*TLA processing of cells, NGS sequencing, and data analysis (excluding copy number and clonality assessments) are ISO/IEC 17025:2017 accredited by the Dutch Accreditation Council RvA, Registration number L671.