Appnotes

Cergentis and its partners have published various application notes about the TLA technology, its applications and the automation of the TLA protocol.

Please select an application to review the corresponding appnotes:

Cell and Gene Therapy
Application note on targeted complete NGS and QC of transgenes and integration sites in upstream cell and gene therapy manufacturing
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Cell and Gene Therapy
Application note on targeted complete NGS and QC of transgenes, integration sites and gene editing in heterogeneous cell and gene therapy products
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Cell Line Development
Targeted Locus Amplification and NGS combined with qPCR-based breakpoint analysis for the assurance of monoclonality in recombinant cell lines
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Cell Line Development
Application of Targeted Locus Amplification for Enhanced Apollo X CHO Clone Screening
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Cell Line Development
Application note: Automated TLA for Targeted Complete Transgene & Integration Sequencing in Pharmaceutical Cell Line Development & Quality Control
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Cell Line Development
Application note on the use of the TLA technology in transgene and integration site sequencing in CHO cell lines.
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Cell Line Development
Application note on Genedata Selector for Efficient and High Quality CHO Cell Line Development - Leveraging TLA for complete sequencing of expression constructs and integration sites
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Genome Editing
Appnote: TLA for complete locus sequencing and quality control of targeted genome editing
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Clinical Genetics
Poster: TLA & Long Read Sequencing: Efficient Targeted Sequencing and Phasing of the CFTR Gene
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Clinical Genetics
Application Note Pacific Biosciences - Targeted Sequencing and Chromosomal Haplotype Assembly Using Cergentis TLA Technology with PacBio SMRT Sequencing.
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Clinical Genetics
Application note on the TLA protocol for isolated genomic DNA.
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Automation
Application note: Automated TLA for Targeted Complete Transgene & Integration Sequencing in Pharmaceutical Cell Line Development & Quality Control
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Transgenic Models
Application note on TLA-based transgene and -integration site sequencing.
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Leukemia
Application note on the application of TLA in gene fusion detection in pediatric leukemia
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Leukemia
Application note on MRD testing using TLA data
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Solid Tumors
Robust detection of structural variants and single nucleotide variants in FFPE
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TLA comparison
See how TLA compares to conventional approaches such as WGS and FISH
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Application notes about TLA
Read application notes about the TLA Technology, published by Cergentis and its partners.
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Publications about TLA
View the publications by various customers and partners who have used TLA in their work.
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Webinars about TLA
Watch webinars to find out more information about TLA and its uses.
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For Research Use Only.Not for use in diagnostic procedures.

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